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Friday, September 21st, 2007A 1mg tablet preparation of finasteride has been licensed as a prescription only medicine for the treatment of male pattern hair loss. The product, called Propecia, has not yet been launched by its manufacturer, Merck Sharp & Dohme (Best Hair Loss Treatment MSD).
Propecia is licensed to increase Treatment For Hair Loss hair growth and prevent further loss of hair in the treatment of male pattern hair loss. The drug is not indicated in women.
MSD says that it is in discussion with the Department of Health about the product’s prescription status. Buy Hair Loss Product A spokeswoman Treatment For Hair Loss for MSD told The Journal on October 25 that the Buy Finasteride company would prefer the drug to be available only on private prescription but the decision Best Hair Loss Treatment regarding Buy Hair Loss Product its classification was for the Government. According to MSD, the Secretary Treatment For Hair Loss of State is expected to consult advisory committees before deciding whether buy Propecia should be categorised in Schedule Buy Finasteride 10 or 11 of the NHS (General Medical Services) Regulations 1992. Schedule 10 drugs (the “black list”) may only be supplied on private, and not NHS, Best Hair Loss Treatment prescriptions. Schedule 11 drugs can be supplied on NHS prescriptions but only for defined conditions. Buy Hair Loss Product
Finasteride, at a higher 5mg strength, is currently used to treat benign prostatic hyperplasia. Dr Julian Cole (Buy Finasteride medical affairs director, MSD) told The Journal on October 26 that MSD did not Best Hair Loss Treatment expect buy Propecia to cause any prostate problems. There were Buy Hair Loss Product “marginal” decreases in levels of serum prostate-specific Treatment For Hair Loss antigen (PSA) but these were not “relevant”. (PSA increases with prostate size and is elevated in prostate cancer.) Dr Cole said that there was “no issue” of treatment with Propecia masking the diagnosis of prostate cancer through its effects on PSA levels. Best Hair Loss Treatment
Finasteride inhibits type II Buy Finasteride 5-alpha-reductase enzyme. This inhibition blocks the peripheral conversion of testosterone to dihydrotestosterone (DHT). Hair follicles contain type II 5-alpha-reductase. Increased levels of DHT result in miniaturisation of hair follicles Buy Hair Loss Product which is seen in the bald areas of men with male pattern hair loss. Hair loss is not seen in men Best Hair Loss Treatment with a genetic deficiency of type II 5-alpha-reductase. MSD says that Buy Finasteride these factors suggest a link between Buy Hair Loss Product male pattern baldness and the presence of DHT. Finasteride is reported to cause a rapid decrease in levels of DHT, producing a significant response within 24 hours. Treatment For Hair Loss
Taking finasteride can stop further hair loss and, in some cases, allow re-growth of hair, the company says. It reports that in phase III clinical trials involving 1,879 men with mild to moderate hair loss, 86 per cent Best Hair Loss Treatment of men treated with finasteride 1mg daily for 12 months either maintained or showed an increase in the number of hairs on their head. At Buy Hair Loss Product 24 months, dermatologists rated 66 per cent Treatment For Hair Loss of those treated with Propecia to have increased hair growth compared with only 7 per cent of the control group. MSD says that the hair grown as a result of treatment with Propecia is normal and not downy. It adds that an improvement of the quality of hair was seen in year two of treatment, according to Buy Finasteride photographic and patient assessment. Buy Hair Loss Product
The prescribing information for the drug notes that a small number of men have experienced minor side effects Best Hair Loss Treatment including decreased libido and erectile dysfunction (reported in less than Buy Finasteride 1 per cent of men). These effects are usually reversible on stopping treatment and sometimes stop when treatment is continued. The drug is reported to have no effect on the growth of body hair.
Chronic treatment
MSD says that once daily treatment for three to six months is required before evidence of stabilisation of hair loss can be seen. Treatment For Hair Loss If treatment is stopped, the beneficial effects begin Buy Finasteride to reverse after six months and return to baseline by nine to 12 months. Treatment should Buy Hair Loss Product be started when hair thinning has become apparent and would not be of use in men with severe hair loss.
The only other licensed product Best Hair Loss Treatment available to treat hair loss is topical minoxidil. MSD says that it has not compared the effects of Propecia with those of minoxidil, nor the combined effects of the two agents.Buy Finasteride
What is male hair loss (male pattern baldness Buy Hair Loss Product /androgenic alopecia)?
Male hair loss is the most common type of hair loss. It is caused by increased sensitivity to male sex hormones (androgens) in certain parts of the scalp, and is passed on from generation to generation. Best Hair Loss Treatment
In the past, baldness was often Treatment For Hair Loss seen as something unfortunate or undesirable. However, this attitude has changed over the years and nowadays a clean-shaven head is usually Buy Finasteride considered both fashionable and attractive.
What causes male hair loss?Buy Hair Loss Product
Some men have areas on the scalp that are very sensitive to the male sex hormones that circulate in men’s blood. The hormones make the hair follicles - from which hair grows - shrink. Eventually, they become so small that they cannot replace lost hairs. The follicles are still alive, but are no longer Buy Hair Loss Product able to perform their task.
The condition usually starts in Best Hair Loss Treatment men aged 20 to 30 and follows a typical pattern. First, a receding hairline develops, and gradually the hair on top of the head also begins to thin. Eventually, the two Buy Finasteride balding Treatment For Hair Loss areas meet to form a typical U-shape around the back and sides of the head. The hair that remains is often finer, and does not grow as quickly as it used to.
Can male hair loss be prevented?
Male hair loss is Buy Finasteride genetically determined (passed on from parents). Although a doctor can offer medical treatment to Treatment For Hair Loss improve the condition, this may have side effects.Buy Hair Loss Product
Oral finasteride is available in 5mg dosage under the brand name Proscar or in 1 mg dosage under the brand name Propecia™. Proscar was first Best Hair Loss Treatment available in the market as a the treatment of benign prostate enlargement. It is an oral medication. It was subsequently discovered that people who have been using Proscar also noticed that drug has positive effects Buy Hair Loss Product on people with hair loss. Merck & Co started clinical testing in the early 90s to evaluate the effectiveness of Finasteride in treating hair loss when taken orally. To minimize the potential of side effects that come with Proscar (5mg finasteride), Merck & Co. conducted clinical Buy Finasteride testing on 1 mg finasteride as a treatment for hair loss.
In November 1997, Merck has satisfied the panel of scientific advisors (to the FDA) that Propecia (1 mg finasteride) is effective in treating hair loss. In December 1997, the FDA officially approved the drug Propeica as Best Hair Loss Treatment the first ever anti-baldness pill in the world. It is now also Buy Hair Loss Product standard Buy Finasteride practice for most dermatologists in the U.S to advise patients to use both Propecia and Rogaine simultaneously for maximum results. Best Hair Loss Treatment
Finasteride is a 5-alpha reductase (5AR) inhibitor. 5-alpha reductase is an enzyme in our body that converts the male hormone testosterone into DHT. DHT is a more potent derivative of testosterone that is believed Buy Hair Loss Product to be the main cause of male pattern baldness. Hair follicles that are Treatment For Hair Loss sensitive to DHT will fall off when exposed to the hormone. Finasteride works by inhibiting the 5 alpha reductase enzyme that is responsible for converting testosterone to DHT. Buy Finasteride

