Archive for September, 2007

Hair Loss Products,Baldness Treatment,Male Hair Loss (Propecia)

Tuesday, September 25th, 2007

Propecia can stop hair loss.
If you are going bald you should consider using Propecia to halt or even reverse your hair loss. While there is no “Hair Loss Cure”, hair loss drugs like Propecia can often stop or even reverse alopecia in most people.Male Hair Loss (Propecia)
Studies have shown that almost 80% of men using Propecia stopped or even reversed their hair loss to some degree.
Propecia (Finasteride) was originally a drug called Proscar, which was used to treat and reduce mens prostate conditions such as benign prostatic hyperplasia (BPH).
Its parent company, Merck & Co., Male Hair Loss (Propecia) soon realized that the drug had a unique side effect - it grew hair on bald men’s heads. In December 22, 1997 the FDA approved Propecia as a hair loss pill. Merck & Co. then marketed the drug as a hair loss treatment under the trade name of Propecia.
How Propecia inhibits DHT and hair loss.
Click here, to see Male Hair Loss (Propecia) an animation how DHT causes hair loss.
Baldness is largely the result of dihydrotestosterone (DHT) interacting with those hair follicles that are genetically vulnerable to their effects.
DHT is essentially the active ingredient or catalyst for the hair loss process. DHT binds with the receptor sites of genetically vulnerable follicles and gradually degrades the follicles ability to produce healthy hair. This eventually results in baldness in the affected areas.
Propecia works by inhibiting the conversion of testosterone into “DHT”. By reducing the DHT present in the scalp the thinning process is slowed and some times even reversed.
Limitations of Propecia.
However, Propecia has not been proven to restore hair in the frontal areas. For reasons yet unknown these drugs, along with Rogaine, generally only work in regrowing thinning hair in crown area of the scalp. Only hair transplant surgery has been successful in restoring hair in the frontal hairline area once it has been lost.
Propecia is also less effective in growing hair in older men. These hair loss drugs work best for men who have been balding for less than five years.
Get a Prescription for Propecia.
Most of the physicians recommended on this site will prescribe Propecia to halt a patient’s hair loss and then restore the hair already lost with hair transplant surgery. These treatments in combination can work synergistically. The drugs work to halt the hair loss, while hair restoration surgery restores what was lost.
Consult with a quality Male Hair Loss (Propecia) physician to get a prescription for Propecia.
Purchase Credible Hair Loss Treatments Online
To learn more about these hair loss treatments or to purchase them online visit the Hair Loss Talk. This site has an excellent reputation online for reliable service and credible content.
Women must NOT USE Propecia
Both Propecia and Avodart are not recommended for use by women or children.
It’s been found that these drugs can cause birth defects. More specifically, these birth defects may occur when large amounts of the drug are absorbed into the body during the period of fetal development.Physicians advise pregnant women to not handle Propecia tablets, as this may Male Hair Loss (Propecia) harm male fetuses. But as of yet, there has not been a single reported case of birth defects caused by handling these tablets.
Furthermore, there’s also no evidence that pregnant women exposed to the semen of Propecia or Avodart patients will risk any birth defects.
Propecia and Avodart are also not advisable for men with liver disease or prostate cancer.
So what are the specific causes of hair loss?
Baldness is largely the result of certain hormones interacting over time with those hair follicles that are vulnerable to their effects.Best Male Hair Loss Product.Both men and women produce “male” hormones. Male Hair Loss (Propecia) The three most common are testosterone, androsteinedione, and dihydrotestosterone (DHT). Hair follicles, as well as the sebaceous glands, contain high levels of an enzyme called 5-alpha-reductase. This enzyme converts testosterone into DHT, via the blood. DHT is the source of most male pattern balding.
In some people, their follicles on the top of the head are genetically vulnerable to baldness. Over time, these genetically vulnerable follicles are acted upon by the hormone DHT. This hormone binds with the receptor sites of these vulnerable follicles and cause the hair follicle to weaken over time. Propecia is a drug that has been shown to slow the creation of DHT and can be helpful in slowing, stopping Male Hair Loss (Propecia) or in some cases, reversing hair loss when it is used early enough.
Hair grows naturally in cycles of approximately 3 to 8 years. At the end of the growth cycle, the hair shaft is shed from the follicle and a new hair grows. With thinning hair or balding, each successive growth cycle is shorter and the hair produced is thinner and finer. This is called ‘miniturization’.
Men and women don’t go bald overnight, it is a slow progression of thinning hair and hair loss that eventually produces baldness. Male Hair Loss (Propecia) In many cases, the balding has progressed to such a stage that hair loss treatment products aren’t enough to reverse the balding process.
Few treatments have the dramatic effect of restoring hair like hair transplant surgery. Click here to learn more about a hair transplant.Male Hair Loss (Propecia)
Not all hair loss is permanent. There are many causes of temporary hair loss that can be treated with diet, stress reduction and a visit to your doctor. Click here to learn about other causes of hair loss. Male Hair Loss (Propecia)

Treatment For Hair Loss,Buy Finasteride,Best Hair Loss Treatment,Buy Hair Loss Product

Friday, September 21st, 2007

A 1mg tablet preparation of finasteride has been licensed as a prescription only medicine for the treatment of male pattern hair loss. The product, called Propecia, has not yet been launched by its manufacturer, Merck Sharp & Dohme (Best Hair Loss Treatment MSD).
Propecia is licensed to increase Treatment For Hair Loss hair growth and prevent further loss of hair in the treatment of male pattern hair loss. The drug is not indicated in women.
MSD says that it is in discussion with the Department of Health about the product’s prescription status. Buy Hair Loss Product A spokeswoman Treatment For Hair Loss for MSD told The Journal on October 25 that the Buy Finasteride company would prefer the drug to be available only on private prescription but the decision Best Hair Loss Treatment regarding Buy Hair Loss Product its classification was for the Government. According to MSD, the Secretary Treatment For Hair Loss of State is expected to consult advisory committees before deciding whether buy Propecia should be categorised in Schedule Buy Finasteride 10 or 11 of the NHS (General Medical Services) Regulations 1992. Schedule 10 drugs (the “black list”) may only be supplied on private, and not NHS, Best Hair Loss Treatment prescriptions. Schedule 11 drugs can be supplied on NHS prescriptions but only for defined conditions. Buy Hair Loss Product
Finasteride, at a higher 5mg strength, is currently used to treat benign prostatic hyperplasia. Dr Julian Cole (Buy Finasteride medical affairs director, MSD) told The Journal on October 26 that MSD did not Best Hair Loss Treatment expect buy Propecia to cause any prostate problems. There were Buy Hair Loss Product “marginal” decreases in levels of serum prostate-specific Treatment For Hair Loss antigen (PSA) but these were not “relevant”. (PSA increases with prostate size and is elevated in prostate cancer.) Dr Cole said that there was “no issue” of treatment with Propecia masking the diagnosis of prostate cancer through its effects on PSA levels. Best Hair Loss Treatment
Finasteride inhibits type II Buy Finasteride 5-alpha-reductase enzyme. This inhibition blocks the peripheral conversion of testosterone to dihydrotestosterone (DHT). Hair follicles contain type II 5-alpha-reductase. Increased levels of DHT result in miniaturisation of hair follicles Buy Hair Loss Product which is seen in the bald areas of men with male pattern hair loss. Hair loss is not seen in men Best Hair Loss Treatment with a genetic deficiency of type II 5-alpha-reductase. MSD says that Buy Finasteride these factors suggest a link between Buy Hair Loss Product male pattern baldness and the presence of DHT. Finasteride is reported to cause a rapid decrease in levels of DHT, producing a significant response within 24 hours. Treatment For Hair Loss
Taking finasteride can stop further hair loss and, in some cases, allow re-growth of hair, the company says. It reports that in phase III clinical trials involving 1,879 men with mild to moderate hair loss, 86 per cent Best Hair Loss Treatment of men treated with finasteride 1mg daily for 12 months either maintained or showed an increase in the number of hairs on their head. At Buy Hair Loss Product 24 months, dermatologists rated 66 per cent Treatment For Hair Loss of those treated with Propecia to have increased hair growth compared with only 7 per cent of the control group. MSD says that the hair grown as a result of treatment with Propecia is normal and not downy. It adds that an improvement of the quality of hair was seen in year two of treatment, according to Buy Finasteride photographic and patient assessment. Buy Hair Loss Product
The prescribing information for the drug notes that a small number of men have experienced minor side effects Best Hair Loss Treatment including decreased libido and erectile dysfunction (reported in less than Buy Finasteride 1 per cent of men). These effects are usually reversible on stopping treatment and sometimes stop when treatment is continued. The drug is reported to have no effect on the growth of body hair.

Chronic treatment
MSD says that once daily treatment for three to six months is required before evidence of stabilisation of hair loss can be seen. Treatment For Hair Loss If treatment is stopped, the beneficial effects begin Buy Finasteride to reverse after six months and return to baseline by nine to 12 months. Treatment should Buy Hair Loss Product be started when hair thinning has become apparent and would not be of use in men with severe hair loss.
The only other licensed product Best Hair Loss Treatment available to treat hair loss is topical minoxidil. MSD says that it has not compared the effects of Propecia with those of minoxidil, nor the combined effects of the two agents.Buy Finasteride
What is male hair loss (male pattern baldness Buy Hair Loss Product /androgenic alopecia)?
Male hair loss is the most common type of hair loss. It is caused by increased sensitivity to male sex hormones (androgens) in certain parts of the scalp, and is passed on from generation to generation. Best Hair Loss Treatment
In the past, baldness was often Treatment For Hair Loss seen as something unfortunate or undesirable. However, this attitude has changed over the years and nowadays a clean-shaven head is usually Buy Finasteride considered both fashionable and attractive.
What causes male hair loss?Buy Hair Loss Product
Some men have areas on the scalp that are very sensitive to the male sex hormones that circulate in men’s blood. The hormones make the hair follicles - from which hair grows - shrink. Eventually, they become so small that they cannot replace lost hairs. The follicles are still alive, but are no longer Buy Hair Loss Product able to perform their task.
The condition usually starts in Best Hair Loss Treatment men aged 20 to 30 and follows a typical pattern. First, a receding hairline develops, and gradually the hair on top of the head also begins to thin. Eventually, the two Buy Finasteride balding Treatment For Hair Loss areas meet to form a typical U-shape around the back and sides of the head. The hair that remains is often finer, and does not grow as quickly as it used to.
Can male hair loss be prevented?
Male hair loss is Buy Finasteride genetically determined (passed on from parents). Although a doctor can offer medical treatment to Treatment For Hair Loss improve the condition, this may have side effects.Buy Hair Loss Product
Oral finasteride is available in 5mg dosage under the brand name Proscar or in 1 mg dosage under the brand name Propecia™. Proscar was first Best Hair Loss Treatment available in the market as a the treatment of benign prostate enlargement. It is an oral medication. It was subsequently discovered that people who have been using Proscar also noticed that drug has positive effects Buy Hair Loss Product on people with hair loss. Merck & Co started clinical testing in the early 90s to evaluate the effectiveness of Finasteride in treating hair loss when taken orally. To minimize the potential of side effects that come with Proscar (5mg finasteride), Merck & Co. conducted clinical Buy Finasteride testing on 1 mg finasteride as a treatment for hair loss.
In November 1997, Merck has satisfied the panel of scientific advisors (to the FDA) that Propecia (1 mg finasteride) is effective in treating hair loss. In December 1997, the FDA officially approved the drug Propeica as Best Hair Loss Treatment the first ever anti-baldness pill in the world. It is now also Buy Hair Loss Product standard Buy Finasteride practice for most dermatologists in the U.S to advise patients to use both Propecia and Rogaine simultaneously for maximum results. Best Hair Loss Treatment
Finasteride is a 5-alpha reductase (5AR) inhibitor. 5-alpha reductase is an enzyme in our body that converts the male hormone testosterone into DHT. DHT is a more potent derivative of testosterone that is believed Buy Hair Loss Product to be the main cause of male pattern baldness. Hair follicles that are Treatment For Hair Loss sensitive to DHT will fall off when exposed to the hormone. Finasteride works by inhibiting the 5 alpha reductase enzyme that is responsible for converting testosterone to DHT. Buy Finasteride

Buy Cheap Propecia-Buy Propecia Online-Cheap Propecia

Wednesday, September 5th, 2007

Pharmacology: Finasteride is a competitive and specific inhibitor of Type II 5 alpha-reductase, an intracellular enzyme that converts the androgen testosterone into dihydrotestosterone (DHT buy propecia). Two distinct isozymes of 5 alpha-reductase are found in mice, rats, monkeys, and humans: Type I and II. Each of these isozymes is differentially expressed in tissues and developmental stages. In humans, Type I 5 alpha-reductase is predominant in the sebaceous glands of most regions of skin, including scalp and liver. Type I 5 alpha-reductase is responsible for approximately one-third of circulating DHT. The Type II 5 alpha-reductase isozyme is primarily found in prostate, seminal vesicles, epididymides and hair follicles as well as liver, and is responsible for two-thirds of circulating DHT. In humans, the mechanism of action of finasteride is based on its preferential inhibition of the Type II isozyme. Using native tissues (scalp and prostate), in vitro binding studies examining the potential of finasteride to inhibit either isozyme revealed a 100-fold selectivity for the human Type II 5 alpha-reductase over Type I isozyme (IC 50=500 and 4.2 nM for Type I and II, respectively cheap propecia online). For both isozymes, the inhibition by finasteride is accompanied by reduction of the inhibitor to dihydrofinasteride and adduct formation with NADP +. The turnover for the enzyme complex is slow (t 1Ä2 approximately 30 days for the Type II enzyme complex and 14 days for the Type I complex, buy chea propecia/finasteride online).

Finasteride has no affinity for the androgen receptor and has no androgenic, antiandrogenic, estrogenic, antiestrogenic, or progestational effects. Inhibition of Type II 5 alpha-reductase blocks the peripheral conversion of testosterone to DHT, resulting in significant decreases in serum and tissue DHT concentrations. Finasteride produces a rapid reduction in serum DHT concentration, reaching 65% suppression within 24 hours of oral dosing with a 1 mg tablet.Buy propecia online

In men with male pattern hair loss (androgenetic alopecia), the balding scalp contains miniaturized hair follicles and increased amounts of DHT compared with hairy scalp. Administration of finasteride decreases scalp and serum DHT concentrations in these men. By this mechanism, finasteride interrupts a key factor in the development of androgenetic alopecia in those patients genetically predisposed.

In a study in 15 healthy male subjects, the mean bioavailability of finasteride 1 mg tablets was 65% (range, 26 to 170%), based on the ratio of AUC relative to a 5 mg i.v. dose infused over 60 minutes. Following the i.v. infusion, mean plasma clearance was 165 mL/min (range, 70 to 279 mL/min Buy cheap propecia) and mean steady-state volume of distribution was 76 L (range, 44 to 96 L). In a separate study, the bioavailability of finasteride was not affected by food.

Approximately 90% of circulating finasteride is bound to plasma proteins. Finasteride has been found to cross the blood-brain barrier.
Indications: For the treatment of male pattern hair loss (androgenetic alopecia, buy cheap propecia online) in men who have mild to moderate scalp hair loss of the vertex and anterior mid-scalp. Clinical studies were conducted in men between 18 to 41 years of age.Buy propecia

Not indicated for use in women (see Warnings) or children.

Contraindications: Pregnancy: Use in women when they are or may potentially be pregnant (see Warnings and Precautions, Exposure to Finasteride–Risk to Male Fetus).

Hypersensitivity to any component of this product.

Not indicated for use in women (see Warnings) or children.
Warnings: Pregnancy and Lactation: Finasteride is not indicated for use in women. Women should not handle crushed or broken finasteride tablets when they are or may potentially be pregnant (see Contraindications or Buy cheap propecia). Because of the ability of Type II 5 alpha-reductase inhibitors such as finasteride to inhibit conversion of testosterone to dihydrotestosterone, finasteride may cause abnormalities of the external genitalia of a male fetus when administered to a pregnant woman. It is not known whether finasteride is excreted in human milk.

Precautions: General: Caution should be used in the administration of finasteride in patients with liver function abnormalities, as finasteride is metabolized in the liver.Online finasteride.

Other causes of alopecia should be ruled out prior to prescribing finasteride. Efficacy and duration of treatment should be assessed periodically by the treating physician.Cheap propecia

Exposure to Finasteride–Risk to Male Fetus: Women should not handle crushed or broken tablets of finasteride when they are or may potentially be pregnant because of the possibility of absorption of finasteride and the subsequent potential risk to a male fetus (see Warnings, Pregnancy and Lactation cheap propecia online). Finasteride tablets are coated and will prevent contact with the active ingredient during normal handling, provided that the tablets have not been broken or crushed.

Postmenopausal Women: Results of a 1-year placebo-controlled study, enrolling 137 healthy post-menopausal women with androgenetic alopecia (age range: 41 to 60 years), showed no benefit of treatment with finasteride 1 mg daily on scalp hair growth.Buy online propecia.

Geriatrics: Clinical studies with finasteride have not been conducted in elderly men with male pattern hair loss.

Children: Finasteride is not indicated for use in children.

Drug Interactions : No drug interactions of clinical importance have been identified. Finasteride does not appear to affect significantly the cytochrome P450-linked drug metabolizing enzyme system. Compounds which have been tested in man have included antipyrine, digoxin, glyburide, propranolol, theophylline and warfarin, and no interactions were found. However, patients on medication with narrow therapeutic indices, such as phenytoin, should be carefully monitored when treatment with finasteride is initiated.Propecia online

Other Concomitant Therapy: Although specific interaction studies were not performed, in clinical studies finasteride doses of 1 mg or more were used concomitantly with ACE inhibitors, acetaminophen, alpha blockers, benzodiazepines, beta blockers, calcium-channel blockers, cardiac nitrates, diuretics, H 2 antagonists, HMG-CoA reductase inhibitors, prostaglandin synthetase inhibitors (NSAIDs, buy propecia online), and quinolones, without evidence of clinically significant adverse interactions.

Drug/Laboratory Test Interactions : In clinical studies with finasteride in men 18 to 41 years of age, the mean value of serum prostate-specific antigen (PSA) decreased from 0.7 ng/mL at baseline to 0.5 ng/mL at month 12. When fina-steride is used in older men who have benign prostatic hyperplasia (BPH), PSA levels are decreased by approximately 50%. Until further information is gathered in men >41 years of age without BPH, consideration should be given to doubling the PSA level in men undergoing this test while taking finasteride.Buy cheap propecia/finasteride online.

Information to Be Provided to the Patients: Patients should be advised that: finasteride is to be used by men only and should be taken daily as prescribed.

In general, daily use for 3 months or more is necessary before hair growth is increased and/or further hair loss is prevented.

The clinical benefits of finasteride can only be maintained with continuous use of finasteride.Cheap propecia buy.

A small number of men may experience less desire to have sex and/or difficulty in achieving an erection. In clinical studies, these side effects disappeared in men who stopped taking finasteride and in most men who continued treatment.

If the patient experiences sustained impairment in sexual function or any other unintended effect, the patient should be advised to consult with the prescribing physician regarding continuation of the medication.

As with all other medications, it is important that any other treating physician(s) be aware of the patient’s use of finasteride.

Women who are or may potentially be pregnant must not use finasteride. They should not handle crushed or broken tablets of finasteride.C+heap propecia

Adverse Effects: Finasteride for male pattern hair loss has been evaluated for safety in clinical studies involving more than 3200 men and is generally well tolerated. In 3 12-month, placebo-controlled, double-blind, multicenter studies of comparable design, the overall safety profiles of finasteride and placebo were similar. Discontinuation of therapy due to any clinical adverse experience occurred in 1.7% of 945 men treated with finasteride and 2.1% of 934 men treated with placebo.Buy propecia online

In these studies, the following drug-related adverse experiences were reported in ³ 1% of men treated with finasteride or placebo, respectively: decreased libido (1.8%, 1.3%), erectile dysfunction (1.3%, 0.7%) and ejaculation disorder (1.2%, 0.7%; primarily decreased volume of ejaculate:[0.8%, 0.4%]). Integrated analysis of clinical adverse experiences showed that during treatment with finasteride, 36 (3.8%) of 945 men had reported one or more of these adverse experiences as compared to 20 (2.1%) of 934 men treated with placebo (p=0.04).Buy propecia.

Resolution of these adverse reactions occurred in men who discontinued therapy with finasteride and in 58% who continued therapy. In a separate study, the effect of finasteride on ejaculate volume was measured and was not different from that seen with placebo.

A sexual function questionnaire was self-administered by patients participating in the 2 vertex baldness trials to detect more subtle changes in sexual function. At month 12, statistically significant differences were found in 3 of 4 domains (sexual interest, erections, and perception of sexual problems, buy finasteride) when compared to placebo. However, no significant difference was seen in the question on overall satisfaction with sex life.

The adverse reactions profile for 547 patients who continued on finasteride for up to 24 months was similar to that observed in the 12-month controlled studies.

The following adverse experiences have been reported in postmarketing use: ejaculation disorder; breast tenderness and enlargement; hypersensitivity reactions including rash, pruritus, urticaria and swelling of the lips and face; and testicular pain.

Finasteride is also in use for the treatment of older men with BPH at 5 times the dosage recommended for male pattern hair loss. Additional adverse reactions that have been reported at the 5 mg dosage in men with BPH are: breast tenderness and enlargement, and hypersensitivity reactions, including lip swelling and rash. In the clinical studies with finasteride, the incidence of these events was not different from placebo.

Laboratory Tests: No difference in standard laboratory parameters was observed between patients treated with placebo or finasteride.

Overdose: Symptoms and Treatment: Patients have received single doses of finasteride up to 400 mg and multiple doses of finasteride up to 80 mg/day for 3 months without adverse reactions.

No specific treatment for overdosage with finasteride is recommended.
Dosage: The recommended dosage is one 1 mg tablet daily. Finasteride may be taken with or without food.

In general, daily use for 3 months or more is necessary before hair growth is increased and/or further hair loss is prevented. Continued use is recommended to obtain maximum benefit. Withdrawal of treatment leads to reversibility of effect within 12 months.

Dosage in Renal Insufficiency: Adjustments in dosage are not necessary in patients with varying degrees of renal insufficiency (creatinine clearances as low as 0.15 mL/s [9 mL/min]) as pharmacokinetic studies did not indicate any change in the disposition of finasteride.Buy propecia

Information for the Patient: See Blue Section–Information for the Patient Propecia.
Supplied: Each tan-colored, 8-sided, film-coated convex tablet,buy cheap propecia with the code MSD 71 on one side and PROPECIA 1 on the other, contains: finasteride 1 mg. Nonmedicinal ingredients: docusate sodium, hydroxypropylcellulose, lactose monohydrate, magnesium stearate, methylhydroxypropylcellulose, microcrystalline cellulose, pregelatinized starch, red ferric oxide, sodium starch glycolate, talc, titanium dioxide and yellow ferric oxide. Blister packages of 28. Store at room temperature 15 to 30°C and protect from moisture.